Directed evolution of P450cin for mediated electron transfer
نویسندگان
چکیده
منابع مشابه
Directed evolution of P450cin for mediated electron transfer.
Directed evolution is a powerful method to optimize enzyme properties for application demands. Interesting targets are P450 monooxygenases which catalyze the stereo- and regiospecific hydroxylation of chemically inert C-H bonds. Synthesis employing P450s under cell-free reaction conditions is limited by low total turnover numbers, enzyme instability, low product yields and the requirement of th...
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ژورنال
عنوان ژورنال: Protein Engineering Design and Selection
سال: 2016
ISSN: 1741-0126,1741-0134
DOI: 10.1093/protein/gzw072